In the Cori Cycle, lactate produced in the muscles is transported to which organ to be converted back to glucose?

In the Cori Cycle, lactate produced in the muscles is transported to which organ to be converted back to glucose?

• A. Liver
• B. Lungs
• C. Kidneys
• D. Muscle

Answer: (A)

Lactate produced by working muscles is carried in the bloodstream to the liver, where it is converted back into glucose through gluconeogenesis. This liver-based process completes the Cori cycle, supplying glucose to muscles again for energy. The lungs handle gas exchange, not glucose synthesis, and while the kidneys can perform some gluconeogenesis, the primary site for the Cori cycle is the liver. The muscle itself mainly produces lactate and does not convert it back to glucose.

Lactate produced by working muscles is carried in the bloodstream to the liver, where it is converted back into glucose through gluconeogenesis. This liver-based process completes the Cori cycle, supplying glucose to muscles again for energy. The lungs handle gas exchange, not glucose synthesis, and while the kidneys can perform some gluconeogenesis, the primary site for the Cori cycle is the liver. The muscle itself mainly produces lactate and does not convert it back to glucose.